"A world-wide prospective study of INC on prognosis and biomarkers in GBS"

A world-wide prospective study of INC on prognosis and biomarkers in GBS

PNS virtual meeting 2020

During the first virtual PNS Annual Meeting, the IGOS Meeting was also held online for the first time. We celebrate a succesful meeting but hope the next PNS meeting will be held in person in the beautiful Copenhagen.More >>

COVID-19 and GBS

As a first step to investigate the possible relationship between COVID-19 and GBS, we have lauched a substudy within IGOS. More >>
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Publications

  1. IGOS protocol: Jacobs, B. C., van den Berg, B. , Verboon, C. , Chavada, G. , Cornblath, D. R., Gorson, K. C., Harbo, T. , Hartung, H. , Hughes, R. A., Kusunoki, S. , van Doorn, P. A., Willison, H. J. and (2017). International Guillain‐Barré Syndrome Outcome Study: protocol of a prospective observational cohort study on clinical and biological predictors of disease course and outcome in Guillain‐Barré syndrome. J Peripher Nerv Syst, 22: 68-76. doi:10.1111/jns.12209
  2. Regional variation: Alex Y Doets, Christine Verboon, Bianca van den Berg, Thomas Harbo, David R Cornblath, Hugh J Willison, Zhahirul Islam, Shahram Attarian, Fabio A Barroso, Kathleen Bateman, Luana Benedetti, Peter van den Bergh, Carlos Casasnovas, Guido Cavaletti, Govindsinh Chavada, Kristl G Claeys, Efthimios Dardiotis, Amy Davidson, Pieter A van Doorn, Tom E Feasby, Giuliana Galassi, Kenneth C Gorson, Hans-Peter Hartung, Sung-Tsang Hsieh, Richard A C Hughes, Isabel Illa, Badrul Islam, Susumu Kusunoki, Satoshi Kuwabara, Helmar C Lehmann, James A L Miller, Quazi Deen Mohammad, Soledad Monges, Eduardo Nobile Orazio, Julio Pardo, Yann Pereon, Simon Rinaldi, Luis Querol, Stephen W Reddel, Ricardo C Reisin, Nortina Shahrizaila, Soren H Sindrup, Waheed Waqar, Bart C Jacobs, IGOS Consortium. Regional variation of Guillain-Barré syndrome. Brain, Volume 141, Issue 10, Oct 2018, Pages 2866–2877, https://doi.org/10.1093/brain/awy232
  3. Guillain-Barré syndrome in Denmark: a population-based study on epidemiology, diagnosis and clinical severity. Al-Hakem, H., Sindrup, S.H., Andersen, H. et al. J Neurol (2019) 266: 440. https://doi.org/10.1007/s00415-018-9151-x
  4. Second IVIg course in Guillain-Barré syndrome with poor prognosis: the non-randomized ISID study, was written by Christine Verboon and members of the IGOS consortium, using the patient data collected in IGOS. The objective of the study was to compare disease course in patients with GBS with a poor prognosis who were treated with one versus two IVIg courses. They showed that outcomes were not better after a second IVIg course.  doi: 10.1136/jnnp-2019-321496
  5. Current treatment practice of Guillain-Barré syndrome, another paper written by Christine Verboon and members of the IGOS consortium, using data from the first 1,300 patients included in IGOS. The objective of the study was to define the current treatment practice of GBS around the world. https://doi.org/10.1212/WNL.0000000000007719
  6. Diagnosis and management of Guillain–Barré syndrome in ten steps, a paper written by Sonja Leonhard and members of the IGOS and IGOS-Zika team. The aim of this paper was to write easy-to-use and internationally applicable guidelines for GBS, using a step-by-step approach. Nature Reviews Neurology Volume 15, pages 671–683 (2019https://doi.org/10.1038/s41582-019-0250-9